Tear lipid layer thickness with eye drops in meibomian gland dysfunction

Tear lipid layer thickness with eye drops in meibomian gland dysfunction

PURPOSE The aim of this study was to evaluate the efficacy of a lipid containing emollient eye drop, Soothe XP, which was reformulated in 2014 with a more stable preservative and buffer system, compared to a control, non-emollient, eye drop (Systane Ultra) in improving lipid layer thickness (LLT) in subjects with dry eye due to meibomian gland dysfunction (MGD). PATIENTS AND METHODS This pros...

Image-based quantitative analysis of tear film lipid layer thickness for meibomian gland evaluation

BACKGROUND Dry eye syndrome is one of the most common ocular diseases, and meibomian gland dysfunction (MGD) is the leading cause of evaporative dry eye syndrome. When the tear film lipid layer becomes thin due to obstructive or hyposecretory meibomian gland dysfunction, the excessive evaporation of the aqueous layer can occur, and this causes evaporative dry eye syndrome. Thus, measuring the l...

Efficacy of an artificial tear emulsion in patients with dry eye associated with meibomian gland dysfunction

OBJECTIVES The aim of the study reported here was to assess the efficacy of an artificial tear emulsion for the treatment of dry eye associated with meibomian gland dysfunction (MGD). METHODS At five clinics, patients completed a 1-week treatment with their habitual topical therapy and then a 4-week treatment with open-label study medication: Systane® Balance Lubricant Eye Drops (Alcon, Alcon...

Decreased tear lipocalin concentration in patients with meibomian gland dysfunction.

BACKGROUND/AIM Recent studies have demonstrated that tear lipocalin (TL) and phospholipids have a crucial role in maintaining tear film stability. The level of TL in patients with meibomian gland dysfunction (MGD) was examined and these data were correlated with the severity of their clinical disorder. METHODS 12 patients with obstructive MGD, 12 patients with seborrhoeic MGD, and 12 age matc...

Meibomian gland dysfunction